Bob Koure
2 min readFeb 6, 2022

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There are two kinds of immunity, serum antibody (the most easily measured, and so what we've been focusing on re vaccination immunity waning over time) and T-cell immunity. The first seems to block infection, although Omicron seems to get by if it isn't high (i.e. boosters). The second means the disease is much less likely to progress to the point of needing hospitalization. I suspect that this is due to the adaptive system fighting the disease rather than the innate, which gets overwhelmed, leading to a 'cytokine storm'.

We're about to have a lot more people with T-cell immunity. Even people with mild/no symptoms wind up with strong T-cell immunity.

So, to reiterate my original comment, we're about to see a large percentage of the population, vaccinated or not, with T-cell immunity.

This doesn't mean that nobody gets the disease, but it means the rate of hospitalization will go down.

IMO, this is good for most of us, but really, really sucks for people with compromised immune systems (although I haven't seen any studies on T-cell immunity of the vaccinated immune-compromised, but I think the inability to mount serum antibodies probably means they're screwed.

This info is all out there, go look at PubMed or other reputable sources (i.e. not social media where both sides are taking extreme positions)

I'd agree that not getting vaccinated is dumb, given the risks - and persuading people not to get vaccinated borders on evil. But the unvaccinated are by-and-large getting infected, so this is mattering less and less (once we're past their hospitalizations, death, and long-Covid (all of which they could have easily avoided)

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Bob Koure
Bob Koure

Written by Bob Koure

Retired software architect, statistical analyst, hotel mgr, bike racer, distance swimmer. Photographer. Amateur historian. Avid reader. Home cook. Never-FBer

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