Now it makes sense how animals — such as migratory birds and hibernator bears — can consume large amounts of fructose in a short period to prepare fat stores ahead for food shortages. It’s simply easier on the brain to binge on fructose-rich foods than it is with glucose.

If you consider that most fructose is routed directly to the liver, and is used there to produce fat (de novo lipegenesis) for these creatures the point of consuming large amounts of fructose is to build up fat stores.

That said, I wonder if this study was done on people who consumed primarily fat and next to no fructose/glucose (e.g. Eskimo peoples eating a traditional diet) what we would find. I suspect we’d see similar to fructose-only consumption.