Interesting study - as is the link with ferroptosis.

The major takeaway from that study and the recent ones on erythritol, if a low or no calorie sweetener is absorbed into the bloodstream, "not metabolized" does NOT mean "no effect".

Also, phospholipase C gamma 1 is interesting. If sucralose can impair it (ligand blocking?) in T-cell proliferation I have to wonder what other processes are being blocked...

I see it's also involved in apoptosis - so totally in your wheelhouse. :-)

Thanks!