Bob Koure
1 min readMay 24, 2022

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If you search for "urolithin a supplement", you'll likely find all sorts of pomegranate products, but no actual urolithin a - which is problematic for 60% of the population (and no way short of a special urine test to tell if your microbiome is converting it - or not.

That said, it seems they used Amazenti's "mitopure" for the studies Gunnar is referencing. Not sure I'll chase if further than that, but knowing what to look for might help someone wanting an actual urolithin a supplement.

BTW/FWIW, the fact that they're actually doing studies is IMO a good thing. They don't need to do this as the FDA does not regulate supplements (although maybe they should - but that's a quite different conversation).

[late addendum]

Given that it seems to promote mitophagy, I'd be curious to see if there were any intellectual effects, particularly in people showing cognitive decline.

In neurons mitochondria are critical, as ATP is constantly being used for the 'pumps' that drive the ionic charge that 'cascades' down the axon.

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Bob Koure
Bob Koure

Written by Bob Koure

Retired software architect, statistical analyst, hotel mgr, bike racer, distance swimmer. Photographer. Amateur historian. Avid reader. Home cook. Never-FBer

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