Bob Koure
1 min readNov 18, 2023

--

I just listened to a Peter Attia's podcast episode with Micky Colins (noted concussion researcher). If you have access to podcasts, I'm pretty sure this is not one of the subscribers-only ones. There's a lot there, notably concussions (medium CTE) come from minor deformation of the brain (either a blow or torque) that causes neurons to stretch a bit. That stretching causes them to eject potassium, and calcium flows back in. The neurons need to reverse this. Calcium pumps work against the 'equilibrium' ionic flow, so they need to be powered, which means the neurons need a lot of glucose and O2 right then - but that calcium vasoconstricts, restricting flow. (personally, I think the issue is mostly O2 as neurons don't have an anaerobic metabolic pathway). Anyway, there's an energy crisis, leading to affected areas “decompensating”.

Possibly more relevant to your article, Collins sees more girls than boys (60/40). He's published quite a bit on concussion, but I don't see a single pub focused on gender differences.

--

--

Bob Koure
Bob Koure

Written by Bob Koure

Retired software architect, statistical analyst, hotel mgr, bike racer, distance swimmer. Photographer. Amateur historian. Avid reader. Home cook. Never-FBer

Responses (2)