For application of the Yamanaka factors to be effective, you'd then have to re-apply the factors that influenced that particular cell in development - or do something functionally equivalent.

Semi-related: Sean Carrol's 'Endless Forms Most Beautiful' is an excellent primmer on embryonic development, in spite of being written before epigenetics were understood. For that, I'd suggest any of Nessa Carey's books. Some of her lectures have made their way to youtube - IMO a great place to start.