As regards dietary saturated fats I've looked at a number of meta-analyses and systematic literature reviews, plus waded through the raw data of a number of studies; I haven't seen any convincing evidence.

There is a connection between dietary saturated fat and serum LDL - but it's the 'large buoyant" type of LDL which does not appear to present an arteriosclerotic risk.

The originator of the theory (Ancel Keys) had no idea there were multiple types of serum cholesterol, let alone a spectrum of size/density in LDL. He claimed to be an epidemiologist, but he was trained in ichthyology - and he committed a cardinal sin of epidemiology: he cherry-picked national correlative data. France doesn't fit the theory? Ignore it, call it the 'French Paradox'. And it wasn't just France.

To be fair, there's good evidence (Gerald Shulman's fMRI work) that flooding serum with both glucose and high triglycerides (no matter the saturation) can lead to insulin resistance in striated muscle tissue, which in humans starts the cascade to systemic IR. (not the same in mice)

Sorry to be 'that guy', particularly as I'm not a bio or med pro, but I have been digging into how the lipids system works for the last couple of years (got interested after listening to a series of conversations Dr Peter Attia had with Dr Tom Dayspring AKA Dr Lipid, been digging since then). Looking at diet-heart studies goes back way before that. Started when I noticed that the raw data did not support the abstract conclusions in the Framingham study - and I do have a stats background.